Pawlity® Premium Liquid Collagen

Hydrolyzed Type I and III collagen peptides are the main structural components of your dog's skin. Type I rebuilds the protective barrier that keeps out allergens and bacteria. Type III repairs damaged tissues in red areas, hot spots, and scratched zones. Together, they provide the essential building blocks for strong and resilient skin.

Collagen makes up to 90% of the connective tissue in the skin. In dogs with chronic dermatitis, natural production decreases with age, making the skin barrier permeable to allergens and bacteria. The low molecular weight hydrolyzed peptides in our liquid formula allow for up to 95% absorption, reaching the deep layers of the skin where true repair occurs.

UC-II® is a patented form of undenatured Type II collagen. Unlike regular collagen supplements, it acts directly on the immune system to reduce systemic inflammation that fuels constant itching. It is clinically studied to soothe inflammatory pathways throughout the body, offering relief without suppressing natural defenses.

Clinical studies show that UC-II® works through a process called "oral tolerance," retraining the overactive immune system that causes chronic itching and skin inflammation. Unlike medications like Apoquel that suppress the immune response, UC-II® naturally modulates it, allowing the body to respond appropriately without side effects.

Quercetin is a flavonoid found in nature with a powerful antihistamine effect. It blocks the release of histamine from cells, calming allergic reactions at their source — without the risks of chemical medications. It is often called the "Apoquel of nature" for its ability to naturally reduce itching and irritation.

When an allergen penetrates the skin, immune cells release histamine, causing itching, redness, and swelling. Quercetin stabilizes the membranes of the cells that produce histamine, preventing excessive release. Unlike chemical antihistamines that block the signal after release, Quercetin acts at the source — preventing the reaction before it starts. This makes it particularly effective in combination with collagen: while collagen rebuilds the barrier, Quercetin soothes ongoing reactions.

Omega-3 fatty acids DHA and EPA are powerful natural anti-inflammatories. They soothe skin irritation from within, support skin hydration, and promote a bright and healthy mantle. They work in synergy with collagen: while collagen rebuilds the structure, Omega-3s calm the inflammation that damages it.

Chronic inflammation is the silent enemy of the skin barrier. Omega-3 EPA and DHA are incorporated into the cell membranes of the skin, where they produce anti-inflammatory molecules called resolvins and protectins. These molecules actively turn off inflammation, allowing the skin to heal instead of remaining in a state of perpetual irritation. Less inflamed skin is skin that repairs faster.

Colostrum is the first nutrient produced by mammal mothers after giving birth, rich in immunoglobulins and growth factors. It strengthens the dog's natural immunity and repairs the intestinal lining. This is essential because 70% of immune function resides in the intestine — a healthy intestine means skin that reacts less to allergens.

There is a direct connection between gut health and skin health, called the gut-skin axis. When the intestinal wall is compromised, inflammatory molecules enter the bloodstream and reach the skin, worsening itching and dermatitis. Colostrum contains IgA immunoglobulins and growth factors that repair the intestinal mucosa, reducing permeability and calming the overactive immune response that manifests as chronic itching.

MSM (Methylsulfonylmethane) is a natural source of organic sulfur, an essential mineral for the production of collagen and keratin. It has a powerful anti-inflammatory action that reduces itching and discomfort, providing quick relief while collagen works to rebuild the skin barrier over time.

Sulfur is the third most abundant mineral in a dog's body and an essential cofactor in the synthesis of collagen and keratin. Without enough sulfur, the body cannot effectively build new connective tissues. MSM provides bioavailable sulfur while also inhibiting pro-inflammatory cytokines, offering a dual mechanism: raw material for reconstruction and relief from inflammation during the process.

Astragalus is an adaptogen used for millennia in traditional medicine for its immune-stimulating properties. It helps the dog's body modulate the immune response — not suppressing it like medications do, but teaching it to react appropriately to allergens without triggering excessive reactions.

In dogs with atopic dermatitis, the immune system is in a state of hyperreactivity: it reacts disproportionately to stimuli that should not be threatening (pollen, mites, grass). Astragalus contains polysaccharides and saponins that modulate the activity of T lymphocytes, rebalancing the immune response. The result: the body stops attacking its own skin and begins to cooperate with the barrier repair process.

Vitamin C is an essential cofactor for collagen production in the dog's body. Without Vitamin C, the body cannot effectively convert collagen peptides into new skin tissues. It is the catalyst that transforms the bricks (collagen) into a solid wall (functional skin barrier).

Vitamin C is essential for the hydroxylation of proline and lysine — the two chemical reactions that stabilize the triple helix of collagen. Without this stabilization, the collagen produced would be weak and unstable. Additionally, Vitamin C is a powerful antioxidant that protects existing collagen from degradation caused by free radicals generated by chronic inflammation.

Zinc is an essential mineral for wound healing and collagen synthesis. It speeds up the healing of areas damaged by scratching — sores, hot spots, reddened areas — and supports the regeneration of the skin barrier. It is particularly important in dogs with chronic lesions that have difficulty healing.

Zinc is involved in more than 300 enzymatic reactions in the body, many of which are related to tissue repair. It activates matrix metalloproteinases — enzymes that remove damaged tissue to make room for reconstruction — and stimulates the proliferation of keratinocytes, the cells that form the skin's outer protective layer. A zinc deficiency drastically slows down skin healing.

Biotin (Vitamin B7) is essential for the health of the coat and skin. It nourishes the hair follicles from the root, reducing hair loss and promoting growth in areas thinned by chronic scratching. A healthy and shiny coat is the visible sign of skin in the process of repair.

Biotin is a cofactor in the production of keratin, the structural protein that makes up hair, nails, and the skin's outer layer. In dogs with chronic dermatitis, constant inflammation depletes biotin reserves, leading to dull, fragile, and sparse hair. Supplementation restores the necessary reserves for healthy keratin production, visible as a denser, shinier, and stronger coat.

Vitamin E is a powerful fat-soluble antioxidant that protects the skin's cell membranes from damage caused by free radicals. Chronic inflammation generates an excess of free radicals that degrade collagen and slow healing — Vitamin E neutralizes these radicals, protecting the rebuilding process.

Free radicals generated by chronic inflammation attack collagen bonds, accelerating their degradation. Vitamin E is incorporated into the cell membranes of the skin where it intercepts free radicals before they can cause damage. This protective effect is synergistic with Vitamin C: while Vitamin C stimulates the production of new collagen, Vitamin E protects existing and newly formed collagen from oxidative destruction.

Hyaluronic acid is a molecule naturally present in the skin that can retain up to 1000 times its weight in water. It keeps the skin hydrated, elastic, and protected. Dry skin cracks and heals more slowly — hyaluronic acid speeds up the repair process by maintaining the optimal skin environment for regeneration.

A dehydrated skin barrier develops micro-cracks that allow allergens and bacteria to enter, triggering inflammation and itching. Hyaluronic acid, integrated from within, reaches the deep layers of the skin where it retains the moisture needed to keep the barrier intact and functional. Well-hydrated skin is skin that defends itself better.